Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name HOXD-AS1
   Synonyms HAGLR, HOXD-AS1, Mdgt
   Region GRCh38_2:176164051-176188958    Sequence
   Ensembl ENSG00000224189
   RefSeq NR_033979
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name ovarian cancer
   ICD-0-3 C56.9  
   Methods qRT-PCR, Western blot, Luciferase reporter assay, in vitro knockdown, RIP
   Sample OC tissues, OC cell lines (Caov-3, SK-OV-3 and OVCAR-3)
   Expression Pattern up-regulated
   Function Description

HOXD-AS1 was observed to be upregulated in both OC tissues and cell lines.HOXD-AS1 was detected to positively regulate the expression of frizzled family receptor 4 (FZD4) by competitively binding to miR-608.

   Pubmed ID 29416930
   Year 2018
   Title HOXD-AS1 promotes cell proliferation, migration and invasion through miR-608/FZD4 axis in ovarian cancer.
   External Links
   Links for  HOXD-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  ovarian cancer Omim       Cosmic

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