Detail
LncRNA Name | HOXD-AS1 |
Synonyms | HAGLR, HOXD-AS1, Mdgt |
Region | GRCh38_2:176164051-176188958 Sequence |
Ensembl | ENSG00000224189 |
RefSeq | NR_033979 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | ovarian cancer |
ICD-0-3 | C56.9 |
Methods | qRT-PCR, Western blot, Luciferase reporter assay, in vitro knockdown, RIP |
Sample | OC tissues, OC cell lines (Caov-3, SK-OV-3 and OVCAR-3) |
Expression Pattern | up-regulated |
Function Description | HOXD-AS1 was observed to be upregulated in both OC tissues and cell lines.HOXD-AS1 was detected to positively regulate the expression of frizzled family receptor 4 (FZD4) by competitively binding to miR-608. |
Pubmed ID | 29416930 |
Year | 2018 |
Title | HOXD-AS1 promotes cell proliferation, migration and invasion through miR-608/FZD4 axis in ovarian cancer. |
External Links |
Links for HOXD-AS1 | GenBank HGNC lncrnadb Noncode |
Links for ovarian cancer | Omim Cosmic |
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