Detail
| LncRNA Name | HOXD-AS1 |
| Synonyms | HAGLR, HOXD-AS1, Mdgt |
| Region | GRCh38_2:176164051-176188958 Sequence |
| Ensembl | ENSG00000224189 |
| RefSeq | NR_033979 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Western blot, Dual luciferase reporter assay, etc. |
| Sample | cervical cancer tissues, cell lines (CaSki, HeLa) |
| Expression Pattern | up-regulated |
| Function Description | downregulation of HOXD-AS1 suppressed chemoresistance of cisplatin-resistant CC cells. we confirmed that HOXD-AS1 can act as a ceRNA to upregulate ZEB1 through miR-130a-3p. HOXD-AS1 enhanced chemoresistance of cisplatin-resistant CC cells through modulating miR-130a-3p/ZEB1 axis |
| Pubmed ID | 29896986 |
| Year | 2018 |
| Title | HOXD-AS1 exerts oncogenic functions and promotes chemoresistance in cisplatin-resistant cervical cancer cells. |
| External Links |
| Links for HOXD-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for cervical cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.