Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name HULC
   Synonyms HULC, HCCAT1, LINC00078, NCRNA00078
   Region GRCh38_6:8435568-9294133    Sequence
   Ensembl ENSG00000251164
   RefSeq NR_004855
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name liver cancer
   ICD-0-3 C22.0  
   Methods qPCR, Western blot, RIP, CHIP, Cells proliferation assay, etc.
   Sample Hep3B cell linesï¼?human liver cancer tissues.
   Expression Pattern up-regulated
   Function Description

This study elucidates a novel mechanism that lncRNA HULC produces a vital function during hepatocarcinogenesis.HULC is negatively associated with expression of PTEN or miR15a in patients of human liver cancer.

   Pubmed ID 29895332
   Year 2018
   Title Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a.
   External Links
   Links for  HULC GenBank       HGNC       lncrnadb       Noncode
   Links for  liver cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.