Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name IGF2-AS
   Synonyms IGF2-AS, IGF2-AS1, IGF2AS, PEG8
   Region GRCh38_11:2140501-2148666    Sequence
   Ensembl ENSG00000099869
   RefSeq NM_016412
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods qPCR, Western blot
   Sample non-small cell lung cancer tissues, cell lines (A549, H23, H226, SW900, H441, H510A, H596, SK-MES-1, H920 and H1299)
   Expression Pattern down-regulated
   Function Description

IGF2AS is downregulated in both NSCLC human tumors and NSCLC cell lines, as well as in stage III or IV tumors. Downregulated IGF2AS was significantly correlated with NSCLC patientsâ?? short overall survival.

   Pubmed ID 28471495
   Year 2017
   Title Prognostic implication and functional role of long noncoding RNA IGF2AS in human non-small cell lung cancer
   External Links
   Links for  IGF2-AS GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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