Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name IGFL2-AS1
   Synonyms NA
   Region GRCh38_19:46189166-46203083    Sequence
   Ensembl ENSG00000268621
   RefSeq NR_135234
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods RNA-seq, qPCR, in vitro knockdown
   Sample metastatic breast tumors and non-tumor tissue, cell lines (MCF-10A, MCF-10AT1 and MCF-10CA1a )
   Expression Pattern down-regulated
   Function Description

IGFL2-AS1 was the most significantly decreased. Our results indicate that this lncRNA plays a role in downregulating its nearest neighbor, IGFL1, and affects migration of breast cancer cells.

   Pubmed ID 28488769
   Year 2017
   Title Selective expression of long non-coding RNAs in a breast cancer cell progression model.
   External Links
   Links for  IGFL2-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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