Detail
| LncRNA Name | KCNQ1OT1 |
| Synonyms | KCNQ1OT1, KCNQ1-AS2, Kncq1, KvDMR1, KvLQT1-AS, LIT1, NCRNA00012 |
| Region | GRCh38_11:2608328-2699994 Sequence |
| Ensembl | ENSG00000269821 |
| RefSeq | NR_002728 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | glioma |
| ICD-0-3 | M9380/3 |
| Methods | qPCR, Western blot, RIP, Luciferase reporter assay |
| Sample | brain tumor tissues, cell lines (U87, U251) |
| Expression Pattern | up-regulated |
| Function Description | KCNQ1OT1 expression was up-regulated in glioma tissues and cells.These results provided a comprehensive analysis of KCNQ1OT1-miR-370-CCNE2 axis in human glioma cells and might provide a novel strategy for glioma treatment. |
| Pubmed ID | 28381990 |
| Year | 2017 |
| Title | Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cellsā?? Malignancy by Activating miR-370/CCNE2 Axis |
| External Links |
| Links for KCNQ1OT1 | GenBank HGNC lncrnadb Noncode |
| Links for glioma | Omim Cosmic |
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