Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name KCNQ1OT1
   Synonyms KCNQ1OT1, KCNQ1-AS2, Kncq1, KvDMR1, KvLQT1-AS, LIT1, NCRNA00012
   Region GRCh38_11:2608328-2699994    Sequence
   Ensembl ENSG00000269821
   RefSeq NR_002728
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name acute myeloid leukemia
   ICD-0-3  M9861/3
   Methods qPCR
   Sample peripheral blood
   Expression Pattern up-regulated
   Function Description

The expression of LncRNA KCNQ1OT1 was associated with NCCN risk grade and survival status in patients with AML. The median overall survival time was significantly shorter in patients with high expression of LncRNA KCNQ1OT1 than that in patients with low expression(P<0.05).

   Pubmed ID 29950199
   Year 2018
   Title [Expression and Clinical Significance of LncRNA KCNQ1OT1 in Patients with Acute Myeloid Leukemia].
   External Links
   Links for  KCNQ1OT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  acute myeloid leukemia Omim       Cosmic

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