Detail
| LncRNA Name | LAMA5-AS1 |
| Synonyms | NA |
| Region | GRCh38_20:62352995-62356480 Sequence |
| Ensembl | ENSG00000228812 |
| RefSeq | NR_109922 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | multiple myeloma |
| ICD-0-3 | C42.1 M9732/3 |
| Methods | Microarray, qRT-PCR |
| Sample | bone marrow |
| Expression Pattern | up-regulated |
| Function Description | the lncRNA ST3GAL6-AS1, ZNF663P, LAMA5-AS1 and RP11-175D17.3 were significantly upregulated in newly diagnosed MM and R/R MM samples compared with IDA controls and MM patients who got CR (P < 0.05) (Fig. 6). There was no significant differences between newly diagnosed MM patients and R/R ones, or MM patients who received CR and IDA controls (P > 0.05)(Fig. 6). the expression level of ST3GAL6-AS1 was associated with D-S (P = 0.021), ISS (P = 0.038), R-ISS stage (P = 0.027), mSMART risk status (P = 0.013) and the percentage of malignant plasma cells in bone marrow (P = 0.031). |
| Pubmed ID | 29459023 |
| Year | 2018 |
| Title | Focusing on long non-coding RNA dysregulation in newly diagnosed multiple myeloma. |
| External Links |
| Links for LAMA5-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for multiple myeloma | Omim Cosmic |
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