Detail
| LncRNA Name | LINC00152 |
| Synonyms | CYTOR, C2orf59, LINC00152, NCRNA00152, MGC4677 |
| Region | GRCh38_2:87454781-87636740 Sequence |
| Ensembl | ENSG00000222041 |
| RefSeq | NR_024204 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | qPCR, RNAi, Western blot, RIP, ChIP, Luciferase reporter assay, Flow cytometry assay etc. |
| Sample | RCC tissues, cell lines (ACHN, Caki-1, Caki-2 and 786-O) |
| Expression Pattern | up-regulated |
| Function Description | LINC00152 expression was up-regulated in RCC tissues compared with adjacent normal tissues.Furthermore, knockdown of LINC00152 inhibited RCC cell proliferation and S phase cell proportion in vitro. Mechanistically,LINC00152 may contribute to RCC progression by epigenetically repressing P16 expression and interacted with miR-205. |
| Pubmed ID | 28337379 |
| Year | 2017 |
| Title | Long intergenic non-coding RNA 00152 promotes renal cell carcinoma progression by epigenetically suppressing P16 and negatively regulates miR-205. |
| External Links |
| Links for LINC00152 | GenBank HGNC lncrnadb Noncode |
| Links for renal cell carcinoma | Omim Cosmic |
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