Detail
LncRNA Name | LINC00152 |
Synonyms | CYTOR, C2orf59, LINC00152, NCRNA00152, MGC4677 |
Region | GRCh38_2:87454781-87636740 Sequence |
Ensembl | ENSG00000222041 |
RefSeq | NR_024204 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | glioblastoma |
ICD-0-3 | C22.0 M8170/3 |
Methods | qPCR, Western blot analysis, RNA-seq |
Sample | U87 cells, brain tumors and normal brain tissue |
Expression Pattern | up-regulated |
Function Description | LINC00152/CYTOR is upregulated in glioblastoma multiforme (GBM) and aggressive wild-type IDH1/2 grade II/III gliomas and upregulation associates with poor patient outcomes.LINC00152 and its homolog MIR4435-2HG associate with aggressive tumors and promote cellular invasion through a mechanism that requires the structural integrity of a hairpin structure. |
Pubmed ID | 29991527 |
Year | 2018 |
Title | LINC00152 Promotes Invasion Through a 3'-hairpin Structure and Associates with Prognosis in Glioblastoma. |
External Links |
Links for LINC00152 | GenBank HGNC lncrnadb Noncode |
Links for glioblastoma | Omim Cosmic |
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