Detail
| LncRNA Name | LINC00152 |
| Synonyms | CYTOR, C2orf59, LINC00152, NCRNA00152, MGC4677 |
| Region | GRCh38_2:87454781-87636740 Sequence |
| Ensembl | ENSG00000222041 |
| RefSeq | NR_024204 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot, etc. |
| Sample | 80 human CRC tissue samples, 40 non?cancerous tissue samples. CRC cell lines (SW480, SW620 , LoVo). |
| Expression Pattern | down-regulation |
| Function Description | Collectively, these findings demonstrate the critical role of lnc00152 in tumor growth and progression in CRC, and identify a novel therapeutic target associated with CRC development and progression. Kaplan?Meyer overall survival curves display higher lnc00152 levels in patients with colorectal cancer (CRC) with lower survival times (log?rank test, P=0.047). However, further clarifications of the systemic correlation between miRNAs and lncRNAs are required. |
| Pubmed ID | 29956750 |
| Year | 2018 |
| Title | Long non?coding RNA 00152 functions as a competing endogenous RNA to regulate NRP1 expression by sponging with miRNA?206 in colorectal cancer. |
| External Links |
| Links for LINC00152 | GenBank HGNC lncrnadb Noncode |
| Links for colorectal cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.