Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name LINC00210
   Synonyms LINC00210, RP11-72L13.1
   Region GRCh38_1:217892900-217920804    Sequence
   Ensembl ENSG00000231814
   RefSeq NR_048550
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods microarray, qPCR, RNAi, Western blot etc.
   Sample cell lines (A549, CDDP etc.)
   Expression Pattern up-regulated
   Function Description

For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP. Cisplatin resistance in non-small-cell lung cancer cells may relate to the changes in noncoding RNAs. Among these, AK126698 appears to confer cisplatin resistance by targeting the Wnt pathway.

   Pubmed ID 23741487
   Year 2013
   Title The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell.
   External Links
   Links for  LINC00210 GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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