Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name LINC00324
   Synonyms C17orf44, NCRNA00324, FLJ34790, MGC104931
   Region GRCh38_7:8220642-8224043    Sequence
   Ensembl ENSG00000178977
   RefSeq NR_026951
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR, Western blot, RIP, etc.
   Sample gastric cancer tissues, cell lines (SGC7901, BGC823, MGC803, AGS, GES-1)
   Expression Pattern up-regulated
   Function Description

The overexpression of LINC00324 was correlated with advanced TNM stage, larger tumor size, and lymph node metastasis as well as poor prognosis. LINC00324 could combine with the RNA-binding protein (RBP) human antigen R (HuR) and thus stabilize the expression of FAM83B.

   Pubmed ID 29915327
   Year 2018
   Title Long intergenic non-coding RNA 00324 promotes gastric cancer cell proliferation via binding with HuR and stabilizing FAM83B expression.
   External Links
   Links for  LINC00324 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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