Detail
LncRNA Name | LINC00339 |
Synonyms | LINC00339, HSPC157, NCRNA00339 |
Region | GRCh38_1:22024558-22031223 Sequence |
Ensembl | ENSG00000218510 |
RefSeq | NR_023918 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | glioma |
ICD-0-3 | M9380/3 |
Methods | qPCR, Western blot, Luciferase reporter assay etc. |
Sample | cell lines (U87,U251), glioma tissues |
Expression Pattern | up-regulated |
Function Description | Knockdown of LINC00339 inhibited glioma cell proliferation, migration, invasion, and tube formation,meanwhile downregulating the expression of VM-related molecular MMP-2 and MMP-14.TWIST1 upregulated the promoter activities of MMP-2 and MMP-14. |
Pubmed ID | 29499931 |
Year | 2017 |
Title | Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis. |
External Links |
Links for LINC00339 | GenBank HGNC lncrnadb Noncode |
Links for glioma | Omim Cosmic |
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