Detail
| LncRNA Name | LINC00673 |
| Synonyms | LINC00673, HI-LNC75, HILNC75, LUCAIR1, SLNCR, SLNCR1, ERRLR01 |
| Region | GRCh38_17:72403322-72592804 Sequence |
| Ensembl | NA |
| RefSeq | NR_036488 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | tongue squamous cell carcinoma |
| ICD-0-3 | C02 M8070/3 |
| Methods | qPCR, RNAi, Cell migration and invasion assay, ISH etc. |
| Sample | TSCC tissues, cell lines (Tca8113 and Cal27) |
| Expression Pattern | up-regulated |
| Function Description | LINC00673 was significantly upregulated in TSCC samples. Then we examined LINC00673 expression in 202 TSCC tissue specimens, LINC00673 is highly expressed in a significant proportion of human TSCC biopsies and correlates with poor prognosis. Knockdown LINC00673 significantly inhibited the cell invasion and migration capability in TSCC cells. |
| Pubmed ID | 28039470 |
| Year | 2017 |
| Title | Overexpression long non-coding RNA LINC00673 is associated with poor prognosis and promotes invasion and metastasis in tongue squamous cell carcinoma. |
| External Links |
| Links for LINC00673 | GenBank HGNC lncrnadb Noncode |
| Links for tongue squamous cell carcinoma | Omim Cosmic |
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