Detail
| LncRNA Name | LINC00673 |
| Synonyms | LINC00673, HI-LNC75, HILNC75, LUCAIR1, SLNCR, SLNCR1, ERRLR01 |
| Region | GRCh38_17:72403322-72592804 Sequence |
| Ensembl | NA |
| RefSeq | NR_036488 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | RNA-seq, qPCR |
| Sample | breast cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | We identified lnc00673 (ERRLR01) as a marker of overall survival (OS) in breast cancer patients.ERRLR01 levels were elevated in triple-negative breast cancer (TNBC) as compared with Luminal-A,Luminal-B, and HER2 breast cancer subtypes. ERRLR01 levels were also inversely correlated with breast cancer survival across all breast cancer patients.OS in ERa-tumors correlated with negative overall survival,while in ERa+ tumors,ERRLR01 correlated with positive outcomes.This suggests ERRLR01 is modulated by hormone signaling in breast cancer.ERRLR01 correlated with distinct pathways including epithelial development and cellular differentiation. |
| Pubmed ID | 28795861 |
| Year | 2017 |
| Title | linc00673 (ERRLR01) is a prognostic indicator of overall survival in breast cancer. |
| External Links |
| Links for LINC00673 | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
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