Detail
| LncRNA Name | LINC00858 |
| Synonyms | LINC00858 |
| Region | GRCh38_10:84279980-84294659 Sequence |
| Ensembl | ENSG00000229404 |
| RefSeq | NR_038220 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | osteosarcoma |
| ICD-0-3 | M9180/3 |
| Methods | qPCR, Western blot, RIP, etc. |
| Sample | osteosarcoma tissues, cell lines (MG-63, U2OS, 143 B, Saos-2, hFOB) |
| Expression Pattern | up-regulated |
| Function Description | In further experiments, LINC00858 was identified to sponge miR-139 to form RNA-induced silencing complex (RISC) using luciferase reporter assay and RNA immunoprecipitation (RIP). these data prove that LINC00858/miR-139/CDK14 axis promotes the tumorigenesis of osteosarcoma. |
| Pubmed ID | 29944887 |
| Year | 2018 |
| Title | Long noncoding RNA LINC00858 promotes osteosarcoma through regulating miR-139-CDK14 axis. |
| External Links |
| Links for LINC00858 | GenBank HGNC lncrnadb Noncode |
| Links for osteosarcoma | Omim Cosmic |
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