Detail
| LncRNA Name | LINC00961 |
| Synonyms | SPAAR, LINC00961, SPARï¼?lin-RECK-3 |
| Region | GRCh38_9:35909483-35937153 Sequence |
| Ensembl | ENSG00000235387 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C56.9 |
| Methods | PCR, Western blot analysis |
| Sample | Human NSCLC cell lines (A549 and H226) lung cancer tissues( LUAD tumor and LUSC tumor tissues) compared with the periâ??tumor tissues and the healthy normal controls |
| Expression Pattern | down-regulated |
| Function Description | it was significantly reduced in human non-small cell lung cancer (NSCLC) tissues. upregulation of LINC00961 repressed proliferating cell nuclear antigen expression and increased Bax expression, indicating that it acts as an important pro-apoptosis gene. Conversely, inhibition of LINC00961 induced proliferating cell nuclear antigen expression and restrained Bax protein levels. |
| Pubmed ID | 30010215 |
| Year | 2018 |
| Title | Long noncoding RNA LINC00961 inhibits cell proliferation and induces cell apoptosis in human non-small cell lung cancer. |
| External Links |
| Links for LINC00961 | GenBank HGNC lncrnadb Noncode |
| Links for non small cell lung cancer | Omim Cosmic |
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