Detail
| LncRNA Name | LINC01060 |
| Synonyms | NA |
| Region | GRCh38_4:188400736-188681051 Sequence |
| Ensembl | ENSG00000249378 |
| RefSeq | NR_033869 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | microarray, RIP, etc. |
| Sample | pancreatic cancer tissues, cell lines (PANC-1, MIA-PaCa-2, ASPC-1, SW1990, BXPC-3, CFPAC-1, Panc 03.27, HPDE) |
| Expression Pattern | down-regulated |
| Function Description | Lower Linc01060 expression in pancreatic cancer tissues was significantly associated with a poor prognosis. Linc01060 inhibited pancreatic cancer proliferation and invasion in vitro and in vivo. These data demonstrate that Linc01060 plays a key role in suppressing pancreatic cancer progression by regulating vinculin expression. |
| Pubmed ID | 29913236 |
| Year | 2018 |
| Title | Loss of Linc01060 induces pancreatic cancer progression through vinculin-mediated focal adhesion turnover. |
| External Links |
| Links for LINC01060 | GenBank HGNC lncrnadb Noncode |
| Links for pancreatic cancer | Omim Cosmic |
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