Detail
| LncRNA Name | LINC01133 |
| Synonyms | lncRNA-PAGBC |
| Region | GRCh38_1:159961218-159984750 Sequence |
| Ensembl | ENSG00000224259 |
| RefSeq | NR_038849 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | osteosarcoma |
| ICD-0-3 | M9180/3 |
| Methods | qPCR |
| Sample | osteosarcoma tissues, cell lines (MG63, Saos-2, HOS, and U2-OS) |
| Expression Pattern | up-regulated |
| Function Description | we found that the expression level of LINC01133 was statistically upregulated in OS tumor tissue and cell lines compared to noncancerous tissues and a normal human osteoplastic cell line. In summary, our study discovered that lncRNA LINC01133 aggravates the proliferation, migration, and invasion of OS by sponging miR-422a, which provides a novel insight in the tumorigenesis of OS. |
| Pubmed ID | 28390115 |
| Year | 2017 |
| Title | Long Noncoding RNA LINC01133 Functions as an miR-422a Sponge to Aggravate the Tumorigenesis of Human Osteosarcoma |
| External Links |
| Links for LINC01133 | GenBank HGNC lncrnadb Noncode |
| Links for osteosarcoma | Omim Cosmic |
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