Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name LINC01133
   Synonyms lncRNA-PAGBC
   Region GRCh38_1:159961218-159984750    Sequence
   Ensembl ENSG00000224259
   RefSeq NR_038849
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name esophageal squamous cell cancer
   ICD-0-3  
   Methods qRT-PCR ect.
   Sample ESCC cell lines (KYSE-140, KYSE-150, KYSE-180, KYSE-30, KYSE-410, KYSE-510, KYSE-520, EC-18, and HKESC1) and an immortalized esophageal epithelial cell line (NE-1), ESCC tissues and paired normal tissues
   Expression Pattern down-regulated
   Function Description

LINC01133 expression levels were frequently lower in ESCC tissues and cell lines than in paired normal tissues and an immortalized esophageal epithelial cell line, respectively. LINC01133 was an independent protective factor and had an anti-tumor effect in the early stage of ESCC development.drinking status in our cohort impaired the predictive accuracy of LINC01133 for patients with ESCC

   Pubmed ID 30007982
   Year 2018
   Title Predictive Value of LINC01133 for Unfavorable Prognosis was Impacted by Alcohol in Esophageal Squamous Cell Carcinoma.
   External Links
   Links for  LINC01133 GenBank       HGNC       lncrnadb       Noncode
   Links for  esophageal squamous cell cancer Omim       Cosmic

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