Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name LINC02471
   Synonyms AC079630.2
   Region GRCh38_12:40156113-40211419    Sequence
   Ensembl ENSG00000223914
   RefSeq NR_146526
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name papillary thyroid cancer
   ICD-0-3  M8260/3
   Methods Microarray, etc.
   Sample 318 papillary thyroid carcinoma (PTC) tissues, 35 normal thyroid gland tissues
   Expression Pattern Differential expression
   Function Description

According to multivariate Cox analysis, the combination of two DEGs (METTL7B and KCTD16) and two DElncRNAs (LINC02454 and LINC02471) could predict the outcome in a more exact way. In conclusion, top DEGs and DElncRNAs could raise diagnosis of PTC in indeterminate FNAB specimens, and some could function as molecule biomarkers for tumor progression and prognosis. The prognostic role of these factors was examined via Kaplan-Meier method, and the log-rank test was conducted to contradistinguish survival time.

   Pubmed ID 29968931
   Year 2018
   Title Role of differentially expressed genes and long non-coding RNAs in papillary thyroid carcinoma diagnosis, progression, and prognosis.
   External Links
   Links for  LINC02471 GenBank       HGNC       lncrnadb       Noncode
   Links for  papillary thyroid cancer Omim       Cosmic

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