Detail
| LncRNA Name | LINC-PINT |
| Synonyms | LINC-PINT, LincRNA-Pint, MKLN1-AS1, PINT, FLJ43663 |
| Region | GRCh38_7:130938963-131110176 Sequence |
| Ensembl | ENSG00000231721 |
| RefSeq | NR_015431 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, ISH etc. |
| Sample | pancreatic cancer tissues, blood |
| Expression Pattern | down-regulated |
| Function Description | Linc-pint expression is lower in plasma samples from PCa patients than from healthy individuals. Linc-pint levels are lower in PCa tumors than in adjacent tissues, carcinoma of the ampulla of Vater (CAV) and cholangiocarcinoma (CCA), and suggest that Linc-pint could be used for distinguishing the cause of malignant obstructive jaundice. Low plasma Linc-pint levels correlate with tumor recurrence, while low tumor Linc-pint levels correlate with poor prognosis for PCa patients after pancreatectomy. |
| Pubmed ID | 27708234 |
| Year | 2016 |
| Title | Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer. |
| External Links |
| Links for LINC-PINT | GenBank HGNC lncrnadb Noncode |
| Links for pancreatic cancer | Omim Cosmic |
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