Detail
| LncRNA Name | LINC-PINT |
| Synonyms | LINC-PINT, LincRNA-Pint, MKLN1-AS1, PINT, FLJ43663 |
| Region | GRCh38_7:130938963-131110176 Sequence |
| Ensembl | ENSG00000231721 |
| RefSeq | NR_015431 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | microarray, qPCR etc. |
| Sample | prostate cancer tissues, cell lines (LNCaP) |
| Expression Pattern | up-regulated |
| Function Description | Five lncRNAs, RP1-4514.2, SUZ12P1, SNHG5, LINC01138, and SNHG1, were down-regulated under DHT treatment. Five lncRNAs, KLKP1, LINC00969, LINC-PINT, TUG1 and MIR17HG, were up-regulated under DHT treatment. Notably, RP1-4514.2 and LINC01138 were induced and KLKP1 was reduced over 2 fold after AR silenced, suggesting the involvement of AR in androgen-mediated regulation of these lncRNAs expressions. |
| Pubmed ID | 27556357 |
| Year | 2016 |
| Title | Identification of androgen-responsive lncRNAs as diagnostic and prognostic markers for prostate cancer. |
| External Links |
| Links for LINC-PINT | GenBank HGNC lncrnadb Noncode |
| Links for prostate cancer | Omim Cosmic |
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