Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name linc-POU3F3
   Synonyms POU3F3, BRN1, OTF8, brain-1
   Region GRCh38_2:104855511-104858574    Sequence
   Ensembl ENSG00000198914
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colon cancer
   ICD-0-3 C18  
   Methods qPCR
   Sample cell lines (HCT-116, HT-29)
   Expression Pattern differential expression
   Function Description

RNA secretion into the bloodstream; we have shown for the first time that the treatment of HCT-116 and HT-29 colon cancer cells with two anti-cancer agents (doxycycline or 3, 3'-diindolylmethane) results in profound changes in the intracellular content of several lnc RNAs

   Pubmed ID 29116072
   Year 2017
   Title Treatment with anti-cancer agents results in profound changes in lncRNA expression in colon cancer cells
   External Links
   Links for  linc-POU3F3 GenBank       HGNC       lncrnadb       Noncode
   Links for  colon cancer Omim       Cosmic

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