Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name linc-POU3F3
   Synonyms POU3F3, BRN1, OTF8, brain-1
   Region GRCh38_2:104855511-104858574    Sequence
   Ensembl ENSG00000198914
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name esophageal squamous cell cancer
   ICD-0-3  
   Methods microarray, qPCR etc.
   Sample ESCC tissues
   Expression Pattern up-regulated
   Function Description

Further validation in a larger cohort including 205 ESCC patients, 82 patients suffering from esophagus dysplasia and 210 healthy controls confirmed that increased Linc00152, CFLAR-AS1 and POU3F3 might be potential biomarkers for predicting the early progress. We also revealed that circulating levels of three lncRNAs were associated with poor post-surgery prognosis of ESCC patients.

   Pubmed ID 27855375
   Year 2016
   Title Three Circulating LncRNA Predict Early Progress of Esophageal Squamous Cell Carcinoma.
   External Links
   Links for  linc-POU3F3 GenBank       HGNC       lncrnadb       Noncode
   Links for  esophageal squamous cell cancer Omim       Cosmic

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