Detail
| LncRNA Name | lincRNA-APOC1P1-3 |
| Synonyms | APOC1P1 |
| Region | GRCh38_19:44926804-44931386 Sequence |
| Ensembl | ENSG00000214855 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | microarray, qPCR, RNAi, RNA pull-down assay etc. |
| Sample | breast cancer tissues, cell lines (MCF7, MDA-MB-231, MDA-MB-453, MDA-MB-468) |
| Expression Pattern | up-regulated |
| Function Description | The lincRNA-APOC1P1-3 was overexpressed in breast cancer, which was related to tumor size and hypomethylation in its promoter region. We also found that APOC1P1-3 could directly bind to tubulin to decrease a-tubulin acetylation, to inactivate caspase-3, and to inhibit apoptosis. |
| Pubmed ID | 27228351 |
| Year | 2016 |
| Title | Long intergenic non-coding RNA APOC1P1-3 inhibits apoptosis by decreasing a-tubulin acetylation in breast cancer. |
| External Links |
| Links for lincRNA-APOC1P1-3 | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
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