Detail
LncRNA Name | ANRIL |
Synonyms | CDKN2B-AS1, ANRIL, CDKN2B-AS, CDKN2BAS, NCRNA00089, PCAT12, p15AS |
Region | GRCh38_9:21994778-22121097 Sequence |
Ensembl | ENSG00000240498 |
RefSeq | NR_003529 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✔ |
Cancer Name | prostate cancer |
ICD-0-3 | C61.9 |
Methods | qPCR etc. |
Sample | cell lines (PC3, MEFs, IMR90 etc.) |
Expression Pattern | up-regulated |
Function Description | Here we report that chromobox 7 (CBX7) within the polycomb repressive complex 1 binds to ANRIL, and both CBX7 and ANRIL are found at elevated levels in prostate cancer tissues. |
Pubmed ID | 20541999 |
Year | 2010 |
Title | Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. |
External Links |
Links for ANRIL | GenBank HGNC lncrnadb Noncode |
Links for prostate cancer | Omim Cosmic |
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