Detail
LncRNA Name | lincRNA-p21 |
Synonyms | TP53COR1, linc-p21, lincRNA-p21 |
Region | NA Sequence |
Ensembl | NA |
RefSeq | NA |
Circulating | ✔ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | chronic lymphocytic leukemia |
ICD-0-3 | M9823/3 |
Methods | qPCR, RNAi, Western blot etc. |
Sample | blood |
Expression Pattern | up-regulated |
Function Description | We analyzed its expression in CLL and lymphoma in the context of DNA damage. 24 hours after IR, lincRNA-p21 expression was strongly induced in a p53-dependent manner in a very large set of CLL patients (n = 73).lncRNAs NEAT1 and lincRNA-p21 as novel elements of the p53-dependent DNA damage response machinery in CLL and lymphoma. |
Pubmed ID | 25971364 |
Year | 2015 |
Title | p53-dependent non-coding RNA networks in Chronic Lymphocytic Leukemia. |
External Links |
Links for lincRNA-p21 | GenBank HGNC lncrnadb Noncode |
Links for chronic lymphocytic leukemia | Omim Cosmic |
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