Detail
LncRNA Name | lincRNA-p21 |
Synonyms | TP53COR1, linc-p21, lincRNA-p21 |
Region | NA Sequence |
Ensembl | NA |
RefSeq | NA |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | colorectal cancer |
ICD-0-3 | C19.9 |
Methods | qPCR etc. |
Sample | CRC tissues, cell lines (HCT-116 (p53t/t), HCT-116(p53-/-) etc.) |
Expression Pattern | down-regulated |
Function Description | We discovered that the expression level of lincRNA-p21 was increased by elevated wild-type p53 induced by nutlin-3 in HCT-116 colon cancer cells. The expression level of lincRNA-p21 was significantly lower in CRC tumor tissue when compared with the paired normal tissue from the same patient. |
Pubmed ID | 24012455 |
Year | 2013 |
Title | Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer. |
External Links |
Links for lincRNA-p21 | GenBank HGNC lncrnadb Noncode |
Links for colorectal cancer | Omim Cosmic |
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