Detail
| LncRNA Name | linc-ROR |
| Synonyms | LINC-ROR, ROR, lincRNA-RoR |
| Region | GRCh38_18:57054558-57072119 Sequence |
| Ensembl | ENSG00000258609 |
| RefSeq | NR_048536 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | M8260/3 |
| Methods | qPCR, in vitro knockdown |
| Sample | cell line(TPC1), FFPE tissue |
| Expression Pattern | up-regulated |
| Function Description | ROR was shown to exert regulatory effect in proliferation, invasion, and stemness of gastricc arcinoma stem cells and in breast cancer,pancreatic cancer, hepatocellular cancer, endometrial cancer, and naso- pharyngeal carcinomas.ROR lncRNA had a negative regulatory on miR-145.SiRNA experiments with ROR also led to increased expression of miR-145, supporting the role of ROR as an endogenous miR-145 sponge.There was upregulation of miR-145 after ROR silencing with a specific siRNA. |
| Pubmed ID | 29280051 |
| Year | 2017 |
| Title | Long Non-coding RNA Linc-ROR Is Upregulated in Papillary Thyroid Carcinoma. |
| External Links |
| Links for linc-ROR | GenBank HGNC lncrnadb Noncode |
| Links for papillary thyroid cancer | Omim Cosmic |
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