Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name linc-ROR
   Synonyms LINC-ROR, ROR, lincRNA-RoR
   Region GRCh38_18:57054558-57072119    Sequence
   Ensembl ENSG00000258609
   RefSeq NR_048536
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name esophageal squamous cell cancer
   ICD-0-3  
   Methods qPCR, Western blot, Cell proliferation assay etc.
   Sample ESCC tissues
   Expression Pattern up-regulated
   Function Description

The quantitative real-time RT-PCR results revealed a significant up-regulation of linc-ROR and its variants 2 and 4 in tumor samples of ESCC, compared to their matched non-tumor tissues obtained from the margin of same tumors. Our data also demonstrated a significant up-regulation of variant 4 in high-grade tumor samples, in comparison to the low-grade ones.

   Pubmed ID 27872710
   Year 2016
   Title Linc-ROR and its spliced variants 2 and 4 are significantly up-regulated in esophageal squamous cell carcinoma.
   External Links
   Links for  linc-ROR GenBank       HGNC       lncrnadb       Noncode
   Links for  esophageal squamous cell cancer Omim       Cosmic

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