Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name linc-ROR
   Synonyms LINC-ROR, ROR, lincRNA-RoR
   Region GRCh38_18:57054558-57072119    Sequence
   Ensembl ENSG00000258609
   RefSeq NR_048536
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods qPCR, RNAi, Western blot etc.
   Sample urine, cell lines (SV-HUC, 5637, TCC-SUP, T24, UMUC3, HT1376, J82, and RT4)
   Expression Pattern up-regulated
   Function Description

In comparison to the level of expression of these selected lncRNA and mRNA in the control SV-40 immortalized non-tumorigenic urothelial cell line SV-HUC, we found elevated expression of HOTAIR, HOXA-AS-2, ANRIL, and HOXA13 in T24 UBC cells. While in TCC-SUP UBC cell line we found HOTAIR, HOX-AS-2, linc-RoR, ANRIL and HOXA13 were elevated

   Pubmed ID 26800519
   Year 2016
   Title Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes.
   External Links
   Links for  linc-ROR GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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