Detail
LncRNA Name | linc-ROR |
Synonyms | LINC-ROR, ROR, lincRNA-RoR |
Region | GRCh38_18:57054558-57072119 Sequence |
Ensembl | ENSG00000258609 |
RefSeq | NR_048536 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | pancreatic cancer |
ICD-0-3 | C25 |
Methods | qPCR, RIP etc. |
Sample | cell lines (PANC-1, SW1990) |
Expression Pattern | up-regulated |
Function Description | linc-ROR was up-regulated in PDAC tissues and related to poor prognosis.Mechanistically, we found that linc-ROR functioned as a competing endogenous RNA (ceRNA) to several tumor suppressor microRNAs, particularly some members of let-7 family. |
Pubmed ID | 28580169 |
Year | 2017 |
Title | Endogenous miRNA Sponge LincRNA-ROR promotes proliferation, invasion and stem cell-like phenotype of pancreatic cancer cells |
External Links |
Links for linc-ROR | GenBank HGNC lncrnadb Noncode |
Links for pancreatic cancer | Omim Cosmic |
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