Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name linc-ROR
   Synonyms LINC-ROR, ROR, lincRNA-RoR
   Region GRCh38_18:57054558-57072119    Sequence
   Ensembl ENSG00000258609
   RefSeq NR_048536
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name pancreatic cancer
   ICD-0-3 C25  
   Methods qPCR, RIP etc.
   Sample cell lines (PANC-1, SW1990)
   Expression Pattern up-regulated
   Function Description

linc-ROR was up-regulated in PDAC tissues and related to poor prognosis.Mechanistically, we found that linc-ROR functioned as a competing endogenous RNA (ceRNA) to several tumor suppressor microRNAs, particularly some members of let-7 family.

   Pubmed ID 28580169
   Year 2017
   Title Endogenous miRNA Sponge LincRNA-ROR promotes proliferation, invasion and stem cell-like phenotype of pancreatic cancer cells
   External Links
   Links for  linc-ROR GenBank       HGNC       lncrnadb       Noncode
   Links for  pancreatic cancer Omim       Cosmic

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