Detail
LncRNA Name | linc-ROR |
Synonyms | LINC-ROR, ROR, lincRNA-RoR |
Region | GRCh38_18:57054558-57072119 Sequence |
Ensembl | ENSG00000258609 |
RefSeq | NR_048536 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | lung cancer |
ICD-0-3 | C34 |
Methods | qPCR, Western blot |
Sample | lung cancer tissues, cell line (A549) |
Expression Pattern | up-regulated |
Function Description | Here, qRT-PCR analysis revealed that p53 and ROR were upregulated while miR-145 was downregulated in non-small cell lung cancer (NSCLC) tissues and LCSCs compared to their paired adjacent normal tissues and lung cancer cells (LCCs). Besides, high p53 level, low miR-145 level, and high ROR level were associated with poor prognosis in NSCLC. |
Pubmed ID | 28516515 |
Year | 2017 |
Title | Interaction of lincRNA ROR and p53/miR-145 correlates with lung cancer stem cell signatures |
External Links |
Links for linc-ROR | GenBank HGNC lncrnadb Noncode |
Links for lung cancer | Omim Cosmic |
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