Detail
| LncRNA Name | ANRIL |
| Synonyms | CDKN2B-AS1, ANRIL, CDKN2B-AS, CDKN2BAS, NCRNA00089, PCAT12, p15AS |
| Region | GRCh38_9:21994778-22121097 Sequence |
| Ensembl | ENSG00000240498 |
| RefSeq | NR_003529 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✔ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | melanoma |
| ICD-0-3 | M8720/3 |
| Methods | qPCR etc. |
| Sample | melanoma tissues |
| Expression Pattern | differential expression |
| Function Description | Risk SNPs (rs3217992, A>G; rs1063192, C>T) for coronary disease, stroke, diabetes, melanoma, and glioma were all associated with allelic expression of ANRIL. Our data show that multiple independent sites in the chromosome 9p21 region influence CDKN2A, CDKN2B and ANRIL expression. SNPs associated with disease in GWA studies are all associated with ANRIL expression, indicating that modulation of ANRIL expression mediates susceptibility to a variety of conditions. |
| Pubmed ID | 20386740 |
| Year | 2010 |
| Title | Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression. |
| External Links |
| Links for ANRIL | GenBank HGNC lncrnadb Noncode |
| Links for melanoma | Omim Cosmic |
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