Detail
| LncRNA Name | linc-ROR |
| Synonyms | LINC-ROR, ROR, lincRNA-RoR |
| Region | GRCh38_18:57054558-57072119 Sequence |
| Ensembl | ENSG00000258609 |
| RefSeq | NR_048536 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR |
| Sample | breast cancer tissues, cell lines (MCF-7, MDA-MB-231, SK-BR-3, BT549, MCF10A) |
| Expression Pattern | up-regulated |
| Function Description | Plasma lincRNA-ROR levels were associated with estrogen receptors and lymph node metastasis.Plasma lincRNA-ROR may be a potential biomarker for BC diagnosis and a dynamic monitor.LincRNA-ROR is reportedly overexpressed in triple-negative (ER-, PR-, HER2-) breast cancer and could serve as a biomarker or therapeutic target for improving survival. |
| Pubmed ID | 29090518 |
| Year | 2017 |
| Title | Detection and analysis of circulating large intergenic non-coding RNA regulator of reprogramming in plasma for breast cancer. |
| External Links |
| Links for linc-ROR | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
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