Detail
| LncRNA Name | Linc-USP16 |
| Synonyms | NA |
| Region | GRCh38_21:29024629-29054488 Sequence |
| Ensembl | ENSG00000156256 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | qPCR, Western blot |
| Sample | cell lines (MHCC97H, MHCC97L, HepG2, SMMC-7721, and LO2) |
| Expression Pattern | down-regulated |
| Function Description | Linc-USP16 expression was significantly down-regulated in HCC patient tissues and cell lines. Further functional experiments suggested that Linc-USP16 could directly increase PTEN expression by acting as a competing endogenous RNA (ceRNA) for miR-21 and miR-590-5p. |
| Pubmed ID | 29179215 |
| Year | 2017 |
| Title | Long Non-Coding RNA Linc-USP16 Functions As a Tumour Suppressor in Hepatocellular Carcinoma by Regulating PTEN Expression |
| External Links |
| Links for Linc-USP16 | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
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