Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name ANRIL
   Synonyms CDKN2B-AS1, ANRIL, CDKN2B-AS, CDKN2BAS, NCRNA00089, PCAT12, p15AS
   Region GRCh38_9:21994778-22121097    Sequence
   Ensembl ENSG00000240498
   RefSeq NR_003529
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods microarray, qPCR etc.
   Sample plasma, breast cancer tissues
   Expression Pattern up-regulated
   Function Description

Expression level of these 3 lncRNAs was determined in plasma samples of 60 patients with BC and 40 healthy individuals by performing real-time PCR. As expected, the relative expression of ANRIL, HIF1A-AS2, and UCA1 was significantly higher in patients with TNBC than in patients with NTNBC, which was consistent with the results of microarray analysis.

   Pubmed ID 28248879
   Year 2017
   Title A three-long noncoding RNA signature as a diagnostic biomarker for differentiating between triple-negative and non-triple-negative breast cancers.
   External Links
   Links for  ANRIL GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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