Detail
LncRNA Name | lncARSR |
Synonyms | NA |
Region | NA Sequence |
Ensembl | NA |
RefSeq | NA |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | renal cell carcinoma |
ICD-0-3 | C64.9 |
Methods | qPCR, Western blot, RIP, ChIP, RNA pull-down assay etc. |
Sample | RCC tissues, cell lines (A498, 769P, Ketr-3, Caki-1, Caki-2) |
Expression Pattern | up-regulated |
Function Description | Here we show that long non-coding RNA lncARSR is upregulated in primary renal T-ICs and associated with a poor prognosis of clear cell RCCs (ccRCC). Knockdown of lncARSR attenuates the self-renewal, tumorigenicity and metastasis of renal T-ICs. |
Pubmed ID | 27886176 |
Year | 2016 |
Title | A feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cells. |
External Links |
Links for lncARSR | GenBank HGNC lncrnadb Noncode |
Links for renal cell carcinoma | Omim Cosmic |
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