Detail
| LncRNA Name | lncHERG |
| Synonyms | LOC644794 |
| Region | GRCh38_7:66904120-66906297 Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | glioblastoma |
| ICD-0-3 | M9440/3 |
| Methods | qPCR, Luciferase reporter assay etc. |
| Sample | GBM cell lines (U87, U251, LN229) |
| Expression Pattern | up-regulated |
| Function Description | LncHERG knockdown impaired cell proliferation, migration and invasion while inhibition of miR-940 in the meantime reversed this trend.In conclusion,our study highlights the essential role of lncHERG in glioblastoma by acting as a competing endogenous RNA of miR-940, which may serve as a new prognostic biomarker in glioblastoma. |
| Pubmed ID | 29296221 |
| Year | 2017 |
| Title | Long noncoding RNA lncHERG promotes cell proliferation, migration and invasion in glioblastoma |
| External Links |
| Links for lncHERG | GenBank HGNC lncrnadb Noncode |
| Links for glioblastoma | Omim Cosmic |
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