Detail
| LncRNA Name | lnc-HOST2 |
| Synonyms | CERNA2, HOST2, lncRNA-HOST2, CERNA2 |
| Region | NA Sequence |
| Ensembl | |
| RefSeq | NR_134505 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot etc. |
| Sample | ovarian cancer tissues, cells lines (OVCAR3) |
| Expression Pattern | up-regulated |
| Function Description | The data showed that HOST2 was obviously upregulated in an EOCderived cell line, OVCAR-3, compared with the other tested cell lines, including MKN28, Huh-7, HepG2, McF-7,DU145, A357, MG63, Hep-2, ARK2 and Hela. HOST2 promotes tumor cell migration, invasion and proliferation in epithelial ovarian cancer by working in key aspetcs of biological behaviors. |
| Pubmed ID | 25292198 |
| Year | 2014 |
| Title | LncRNA-HOST2 regulates cell biological behaviors in epithelial ovarian cancer through a mechanism involving microRNA let-7b. |
| External Links |
| Links for lnc-HOST2 | GenBank HGNC lncrnadb Noncode |
| Links for ovarian cancer | Omim Cosmic |
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