Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name lnc-JPH1-7
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name head and neck squamous cell carcinoma
   ICD-0-3 C76.0  M8070/3
   Methods qPCR, RNAi etc.
   Sample cell lines (UMSCC-10B, UMSCC-22B, HN-1, HN-12, HN-30, SCC-4, Cal-27 etc.)
   Expression Pattern up-regulated
   Function Description

We found that elevated lnc-JPH1-7 levels in HNSCCs associated not only with poor prognosis, methyltransferase KMT2D (MLL1) mutation, and concurrent TP53 mutation and 3p deletion, but also significantly correlated to advanced tumor stage. Furthermore, higher median lnc-JPH1-7 expression was observed among HPVnegative patients and patients reporting history of smoking.

   Pubmed ID 27323410
   Year 2016
   Title The non-coding landscape of head and neck squamous cell carcinoma.
   External Links
   Links for  lnc-JPH1-7 GenBank       HGNC       lncrnadb       Noncode
   Links for  head and neck squamous cell carcinoma Omim       Cosmic

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