Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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   LncRNA Name lnc-LCE5A-1
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name pharyngeal cancer
   ICD-0-3 C14  
   Methods RNA-seq, qPCR etc.
   Sample cell lines (HN-1, HN-30)
   Expression Pattern down-regulated
   Function Description

We confirmed the dysregulation of these noncoding RNAs in head and neck cancer cell lines derived from different anatomic sites, and determined that ectopic expression of the two lncRNAs inhibited key EMT and stem cell genes and reduced cellular proliferation and migration.

   Pubmed ID 25904139
   Year 2015
   Title Transcriptome sequencing uncovers novel long noncoding and small nucleolar RNAs dysregulated in head and neck squamous cell carcinoma.
   External Links
   Links for  lnc-LCE5A-1 GenBank       HGNC       lncrnadb       Noncode
   Links for  pharyngeal cancer Omim       Cosmic

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