Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name lncMAPK6
   Synonyms NA
   Region GRCh38_15:51952106-52067372    Sequence
   Ensembl ENSG00000069956
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name liver cancer
   ICD-0-3 C22.0  
   Methods Luciferase reporter assay etc.
   Sample liver cancer tissues
   Expression Pattern up-regulated
   Function Description

MAPK6 was the most highly expressed MAPK component in liver cancer and liver TICs and lncMAPK6 participated in the transcriptional regulation of MAPK6in cis. This work revealed the importance role of MAPK signaling in liver TIC self-renewal and added a new layer for liver TIC and MAPK6 expression regulation.

   Pubmed ID 29764463
   Year 2018
   Title LncMAPK6 drives MAPK6 expression and liver TIC self-renewal.
   External Links
   Links for  lncMAPK6 GenBank       HGNC       lncrnadb       Noncode
   Links for  liver cancer Omim       Cosmic

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