Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name lnc-OC1
   Synonyms FRP, FSL1, OCC1, OCC-1, tsc36, MIR198
   Region GRCh38_3:120392293-120451253    Sequence
   Ensembl ENSG00000163430
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR, Western blot, RIP, Microarray, etc.
   Sample cell lines (Caco-2, HCT116, HT-29, RKO, SW480, SW620 ,HEK-293T)
   Expression Pattern down-regulated
   Function Description

LncRNA OCC-1 can regulate the levels of a large number of mRNAs at post-transcriptional level through modulating RBP HuR stability.

   Pubmed ID 29931370
   Year 2018
   Title Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer.
   External Links
   Links for  lnc-OC1 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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