Detail
| LncRNA Name | lncPARP1 |
| Synonyms | lncPARP1, LINC01703 |
| Region | GRCh38_1: 226083639-226090292 Sequence |
| Ensembl | ENSG00000225518 |
| RefSeq | NR_146920 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 M8170/3 |
| Methods | qPCR, western blot etc. |
| Sample | hepatocellular carcinoma tissue, cell lines (SMMC-7721, HepG2, Huh7, SK-Hep-1, PLC/PRF/5, and Bel-7402) |
| Expression Pattern | up-regulated |
| Function Description | Here, we identified a novel oncogenic lncRNA termed as lncPARP1, which was significantly up-regulated in HCC. Increase in lncPARP1 expression was associated with age, a-fetoprotein (AFP) levels, tumor size, recurrence, and poor prognosis of HCC patients. |
| Pubmed ID | 29776974 |
| Year | 2018 |
| Title | The long noncoding RNA lncPARP1 contributes to progression of hepatocellular carcinoma through up-regulation of PARP1 |
| External Links |
| Links for lncPARP1 | GenBank HGNC lncrnadb Noncode |
| Links for hepatocellular carcinoma | Omim Cosmic |
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