Detail
| LncRNA Name | lncRNA-ATB |
| Synonyms | LOC109207222 |
| Region | NA Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qPCR etc. |
| Sample | PTC tissues, cell lines (IHH-4, TPC-1, K1, HTH83, Nthy-ori 3-1) |
| Expression Pattern | up-regulated |
| Function Description | ATB is upregulated in PTC tissues compared with noncancerous tissues. ATB is upregulated and functions as an oncogene in PTC. Furthermore, lncRNA-ATB may serve as a diagnostic biomarker and therapeutic target for PTC. High-expression of lncRNA-ATB is associated with large tumor size and lymph node metastasis. LncRNA-ATB has been reported to promote cancer metastasis via binding and negatively regulating miR-200 family,and then inducing epithelial-mesenchymal transition22. |
| Pubmed ID | 28770959 |
| Year | 2017 |
| Title | The expression and function of long noncoding RNA lncRNA-ATB in papillary thyroid cancer. |
| External Links |
| Links for lncRNA-ATB | GenBank HGNC lncrnadb Noncode |
| Links for thyroid cancer | Omim Cosmic |
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