Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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   LncRNA Name lncRNA-ATB
   Synonyms LOC109207222
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name renal cell carcinoma
   ICD-0-3 C64.9  
   Methods qPCR
   Sample renal cell carcinoma tissues
   Expression Pattern up-regulated
   Function Description

The expression level of lncRNA-ATB was significantly upregulated in RCC tissues vs. corresponding non-tumor tissues (p<0.01) and the high expression of lncRNA-ATB was significantly associated with histological grade (p=0.008), lymph nodes metastasis (p=0.015), and distant metastasis (p=0.008). Also, Kaplan-Meier analysis indicated patients with high lncRNA-ATB expression that had a significantly shorter overall survival than those with low lncRNA-ATB expression (p<0.001).

   Pubmed ID 28682434
   Year 2017
   Title High expression of long non-coding RNA ATB is associated with poor prognosis in patients with renal cell carcinoma
   External Links
   Links for  lncRNA-ATB GenBank       HGNC       lncrnadb       Noncode
   Links for  renal cell carcinoma Omim       Cosmic

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