Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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   LncRNA Name lncRNA-ATB
   Synonyms LOC109207222
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name pancreatic cancer
   ICD-0-3 C25  
   Methods qPCR etc.
   Sample pancreatic cancer tissues, cell lines (HPDE6c-7)
   Expression Pattern down-regulated
   Function Description

We found that lncRNA-ATB expression was decreased in pancreatic cancer tissues and pancreatic cancer cell lines. Low lncRNA-ATB expression levels were significantly correlated with lymph node metastases, neural invasion, and clinical stage. Moreover, patients with low lncRNA-ATB expression levels exhibited markedly worse overall survival prognoses. Multivariate analysis indicated that decreased lncRNA-ATB expression was an independent predictor of poor prognosis in pancreatic cancer patients.

   Pubmed ID 26482611
   Year 2015
   Title Downregulation of lncRNA-ATB correlates with clinical progression and unfavorable prognosis in pancreatic cancer
   External Links
   Links for  lncRNA-ATB GenBank       HGNC       lncrnadb       Noncode
   Links for  pancreatic cancer Omim       Cosmic

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